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Special Reports Rubric : system components - sample conditioning

Rubrics : liquid analytics - solid analytics - sample conditioning/auxiliary units
Automated sample preparation for the analysis of residues and contaminants
in food and feed as well as for environmental samples and biological matrices


New Sample Loading for the Automated Sample Preparation: Bidirectional SPE

- The robotic system FREESTYLE of LCTech GmbH automatically processes the most difficult matrices in the field of forensic
and toxicology: reliably and without cross-contamination -

The specialist for automated sample preparation
LCTech GmbH has developed a new procedure of sample loading, the bidirectional SPE (solid phase extraction). Thus, even very difficult matrices with smallest sample volumes, like brain, can be processed automatically without supervision over 24 hours and 7 days per week.

Using the bidirectional SPE
the sample is aspirated through the LUER tip into the column. It passes the sorbent from bottom to top and is released directly afterwards into a vial from top to bottom whereas the sample passes the sorbent for the second time.
With this kind of sample loading and releasing the sample never enters the robotic system and a contamination of one sample to the next one can be excluded. Unwanted matrix effects are minimised. The elution of the analytes is possible with only a minimal amount of solvents. The original applied sample is collected in a vial next to the sample vial and is available for further processing if needed.

A cooperation with Dr. T. Stimpfl
of the Medical University of Vienna has shown that the procedure of bidirectional SPE is especially suitable for acidic, neutral or basic analytes in brain tissue or similar matrices. Lipids and proteins make the automated handling of these matrices particularly difficult, as the samples can contaminate the system due to their characteristics.
The risk of cross-contamination is very high, if the samples are loaded with a standard procedure and can only be prevented with intensive rinsing. However with the procedure of bidirectional SPE the user can have the samples processed around the clock, safe and reliable.




Press release LCTech v. 5.2.2016


Bidirectional SPE
Sample Loading for the Automated Sample Preparation



You can see the FREESTYLE robotic system with the new bidirectional SPE procedure for yourself at

analytica 2016
in Munich, Germany,
in hall A2 booth 400



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